Thomas D. Brown Real Estate Associates
Rentals 508-349-2700
300 Route 6
PO Box 2003
Truro, MA 02666

643 Main Street Harwich MA 02645 | MLS #22603623

There are multiple listings for this address:
MLS #22603623 image #0MLS #22603623 image #1MLS #22603623 image #2MLS #22603623 image #3MLS #22603623 image #4MLS #22603623 image #5MLS #22603623 image #6MLS #22603623 image #7MLS #22603623 image #8MLS #22603623 image #9MLS #22603623 image #10MLS #22603623 image #11MLS #22603623 image #12MLS #22603623 image #13MLS #22603623 image #14MLS #22603623 image #15MLS #22603623 image #16MLS #22603623 image #17MLS #22603623 image #18MLS #22603623 image #19MLS #22603623 image #20MLS #22603623 image #21MLS #22603623 image #22MLS #22603623 image #23MLS #22603623 image #24MLS #22603623 image #25MLS #22603623 image #26MLS #22603623 image #27MLS #22603623 image #28MLS #22603623 image #29MLS #22603623 image #30MLS #22603623 image #31MLS #22603623 image #32MLS #22603623 image #33MLS #22603623 image #34MLS #22603623 image #35MLS #22603623 image #36MLS #22603623 image #37MLS #22603623 image #38MLS #22603623 image #39MLS #22603623 image #40MLS #22603623 image #41MLS #22603623 image #42MLS #22603623 image #43
A rare Harwich Center property with space to live, work, create, and tinker! Set on approximately 1.5 acres, this unique offering includes a 6-bedroom main home, separate ADU with its own private driveway and strong rental history, plus a detached mixed-use garage with serious potential. Auto enthusiasts, collectors, contractors, tradespeople, hobbyists, or anyone dreaming of their own workshop will appreciate the space for vehicles, tools, equipment, projects, and storage. The flexible living arrangement also lends itself to multigenerational living, extended family, guests, or potential employee/workforce housing. Outside, a spacious landscaped backyard, multiple sheds, and fire pit create even more possibilities—think additional workshop space, art studio, home bar, hobby room, or private retreat. Whether you’re looking for income potential, room for your passion projects, or a property that can accommodate both living and working, this is anything but ordinary!
Current real estate data for Single Family in Harwich as of Oct 10, 2026
42
Single Family Listed
74
Avg DOM
562
Avg $ / SqFt
$1,340,457
Avg List Price

Property Details

Price:
$1,299,000
MLS #:
22603623
Status:
Active
Beds:
6
Baths:
3
Type:
Single Family
Subtype:
Mixed Use
Neighborhood:
harwich
Listed Date:
Jul 27, 2026
Finished Sq Ft:
2,872
Total Sq Ft:
2,872
Lot Size:
62,291 sqft / 1.43 acres (approx)
Year Built:
1919
HarwichHarwichMonomoy

Schools

School District:
Monomoy

Interior

Appliances
Water Heater
Cooling
Wall Unit(s)
Flooring
Wood, Tile, Carpet
Heating
Oil

Exterior

Building Features
Shelving, Other, Private Yard, Curb Cuts
Construction Materials
Shingle Siding
Lot Features
Cleared, Level
Parking Features
Driveway, Paved
Parking Spots
8
Parking Total
8
Roof
Asphalt
Stories
2

Financial

Tax Year
2026
Taxes
$5,664

Map

Contact Us

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Community

Property Summary

    643 Main Street Harwich MA is a Single Family for sale in Harwich, MA, 02645. It is listed for $1,299,000 and features 6 beds, 3 baths, and has approximately 2,872 square feet of living space, and was originally constructed in 1919. The current price per square foot is $452. The average price per square foot for Single Family listings in Harwich is $562. The average listing price for Single Family in Harwich is $1,340,457. To schedule a showing of MLS#22603623 at 643 Main Street in Harwich, MA, contact your Thomas D Brown R E Associates agent at 508-487-1112.

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Raised in Orleans and now a resident of Truro, Lucy is extremely familiar with life on the Outer Cape. She is experienced in real estate sales on Cape Cod and has been involved in construction, development and real estate for over thirty-five years here on the Outer Cape. She presently handles all facets of marketing for both Brown Associates and Cape Vacation Rentals. Degree in Sales & Marketing; formerly associated with Nickerson Realty Corp. where she handled all phases of land development, a…

More About Lucy
643 Main Street
Harwich, MA
MLS #22605076 image #0MLS #22605076 image #1MLS #22605076 image #2MLS #22605076 image #3MLS #22605076 image #4MLS #22605076 image #5MLS #22605076 image #6MLS #22605076 image #7MLS #22605076 image #8MLS #22605076 image #9MLS #22605076 image #10MLS #22605076 image #11MLS #22605076 image #12MLS #22605076 image #13MLS #22605076 image #14MLS #22605076 image #15MLS #22605076 image #16MLS #22605076 image #17MLS #22605076 image #18MLS #22605076 image #19MLS #22605076 image #20MLS #22605076 image #21MLS #22605076 image #22MLS #22605076 image #23MLS #22605076 image #24MLS #22605076 image #25MLS #22605076 image #26MLS #22605076 image #27MLS #22605076 image #28MLS #22605076 image #29MLS #22605076 image #30MLS #22605076 image #31MLS #22605076 image #32MLS #22605076 image #33MLS #22605076 image #34MLS #22605076 image #35MLS #22605076 image #36MLS #22605076 image #37MLS #22605076 image #38MLS #22605076 image #39MLS #22605076 image #40MLS #22605076 image #41MLS #22605076 image #42MLS #22605076 image #43
A rare Harwich Center property with space to live, work, create, and tinker! Set on approximately 1.5 acres, this unique offering includes a 6-bedroom main home, separate ADU with its own private driveway and strong rental history, plus a detached mixed-use garage with serious potential. Auto enthusiasts, collectors, contractors, tradespeople, hobbyists, or anyone dreaming of their own workshop will appreciate the space for vehicles, tools, equipment, projects, and storage. The flexible living arrangement also lends itself to multigenerational living, extended family, guests, or potential employee/workforce housing. Outside, a spacious landscaped backyard, multiple sheds, and fire pit create even more possibilities—think additional workshop space, art studio, home bar, hobby room, or private retreat. Whether you’re looking for income potential, room for your passion projects, or a property that can accommodate both living and working, this is anything but ordinary!
Current real estate data for Multi Family in Harwich as of Oct 10, 2026
42
Multi Family Listed
74
Avg DOM
562
Avg $ / SqFt
$1,340,457
Avg List Price

Property Details

Price:
$1,299,000
MLS #:
22605076
Status:
Active
Beds:
6
Baths:
3
Type:
Multi Family
Subtype:
Mixed Use
Neighborhood:
harwich
Listed Date:
Jul 27, 2026
Finished Sq Ft:
2,872
Total Sq Ft:
2,872
Lot Size:
62,291 sqft / 1.43 acres (approx)
Year Built:
1919
HarwichHarwichMonomoy

Schools

School District:
Monomoy

Interior

Appliances
Water Heater
Cooling
Wall Unit(s)
Flooring
Wood, Tile, Carpet
Heating
Oil

Exterior

Building Features
Shelving, Other, Private Yard, Curb Cuts
Construction Materials
Shingle Siding
Lot Features
Cleared, Level
Parking Features
Driveway, Paved
Parking Spots
8
Parking Total
8
Roof
Asphalt
Stories
2

Financial

Tax Year
2026
Taxes
$5,664

Map

Contact Us

Send
  

Mortgage Calculator

 

Community

Property Summary

    643 Main Street Harwich MA is a Multi Family for sale in Harwich, MA, 02645. It is listed for $1,299,000 To schedule a showing of MLS#22605076 at 643 Main Street in Harwich, MA, contact your Thomas D Brown R E Associates agent at 508-487-1112.

Similar Listings Nearby

Raised in Orleans and now a resident of Truro, Lucy is extremely familiar with life on the Outer Cape. She is experienced in real estate sales on Cape Cod and has been involved in construction, development and real estate for over thirty-five years here on the Outer Cape. She presently handles all facets of marketing for both Brown Associates and Cape Vacation Rentals. Degree in Sales & Marketing; formerly associated with Nickerson Realty Corp. where she handled all phases of land development, a…

More About Lucy
MLS #22605083 image #0MLS #22605083 image #1MLS #22605083 image #2MLS #22605083 image #3MLS #22605083 image #4MLS #22605083 image #5MLS #22605083 image #6MLS #22605083 image #7MLS #22605083 image #8MLS #22605083 image #9MLS #22605083 image #10MLS #22605083 image #11MLS #22605083 image #12MLS #22605083 image #13MLS #22605083 image #14MLS #22605083 image #15MLS #22605083 image #16MLS #22605083 image #17MLS #22605083 image #18MLS #22605083 image #19MLS #22605083 image #20MLS #22605083 image #21MLS #22605083 image #22MLS #22605083 image #23MLS #22605083 image #24MLS #22605083 image #25MLS #22605083 image #26MLS #22605083 image #27MLS #22605083 image #28MLS #22605083 image #29MLS #22605083 image #30MLS #22605083 image #31MLS #22605083 image #32MLS #22605083 image #33MLS #22605083 image #34MLS #22605083 image #35MLS #22605083 image #36MLS #22605083 image #37MLS #22605083 image #38MLS #22605083 image #39MLS #22605083 image #40MLS #22605083 image #41MLS #22605083 image #42MLS #22605083 image #43
A rare Harwich Center property with space to live, work, create, and tinker! Set on approximately 1.5 acres, this unique offering includes a 6-bedroom main home, separate ADU with its own private driveway and strong rental history, plus a detached mixed-use garage with serious potential. Auto enthusiasts, collectors, contractors, tradespeople, hobbyists, or anyone dreaming of their own workshop will appreciate the space for vehicles, tools, equipment, projects, and storage. The flexible living arrangement also lends itself to multigenerational living, extended family, guests, or potential employee/workforce housing. Outside, a spacious landscaped backyard, multiple sheds, and fire pit create even more possibilities—think additional workshop space, art studio, home bar, hobby room, or private retreat. Whether you’re looking for income potential, room for your passion projects, or a property that can accommodate both living and working, this is anything but ordinary!
Current real estate data for Commercial in Harwich as of Oct 10, 2026
42
Commercial Listed
74
Avg DOM
562
Avg $ / SqFt
$1,340,457
Avg List Price

Property Details

Price:
$1,299,000
MLS #:
22605083
Status:
Active
Beds:
0
Baths:
3
Type:
Commercial
Subtype:
Mixed Use
Neighborhood:
harwich
Listed Date:
Oct 6, 2026
Finished Sq Ft:
2,872
Total Sq Ft:
2,872
Lot Size:
62,291 sqft / 1.43 acres (approx)
Year Built:
1919
HarwichHarwichMonomoy

Schools

School District:
Monomoy

Interior

Appliances
Water Heater
Cooling
Wall Unit(s)
Flooring
Wood, Tile, Carpet
Heating
Oil

Exterior

Building Features
Shelving, Other, Private Yard, Curb Cuts
Construction Materials
Shingle Siding
Lot Features
Cleared, Level
Parking Features
Driveway, Paved
Parking Spots
8
Parking Total
8
Roof
Asphalt
Stories
2

Financial

Tax Year
2026
Taxes
$5,664

Map

Contact Us

Send
  

Mortgage Calculator

 

Community

Property Summary

    643 Main Street Harwich MA is a Commercial for sale in Harwich, MA, 02645. It is listed for $1,299,000 To schedule a showing of MLS#22605083 at 643 Main Street in Harwich, MA, contact your Thomas D Brown R E Associates agent at 508-487-1112.

Similar Listings Nearby

Raised in Orleans and now a resident of Truro, Lucy is extremely familiar with life on the Outer Cape. She is experienced in real estate sales on Cape Cod and has been involved in construction, development and real estate for over thirty-five years here on the Outer Cape. She presently handles all facets of marketing for both Brown Associates and Cape Vacation Rentals. Degree in Sales & Marketing; formerly associated with Nickerson Realty Corp. where she handled all phases of land development, a…

More About Lucy